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Ethnic Differences in Insulin Resistance, Adiponectin Levels and Abdominal Obesity: Haitian Americans and African Americans, with and without Type 2 Diabetes Mellitus

BACKGROUND: Metabolic outcomes of obesity and its associated disorders may not be equivalent across ethnicity and diabetes status. AIM: In this paper, we examined the association of abdominal obesity, by ethnicity and diabetes status, for indicators of glucose metabolism in Blacks. METHODS: A cross...

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Autores principales: Cheema, Amanpreet K., Zarini, Gustavo G., Exebio, Joel, Ajabshir, Sahar, Shaban, Lemia, Antwi, Janet, Vaccaro, Joan A., Huffman, Fatma G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820514/
https://www.ncbi.nlm.nih.gov/pubmed/31667161
http://dx.doi.org/10.9734/bjmmr/2014/10333
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author Cheema, Amanpreet K.
Zarini, Gustavo G.
Exebio, Joel
Ajabshir, Sahar
Shaban, Lemia
Antwi, Janet
Vaccaro, Joan A.
Huffman, Fatma G.
author_facet Cheema, Amanpreet K.
Zarini, Gustavo G.
Exebio, Joel
Ajabshir, Sahar
Shaban, Lemia
Antwi, Janet
Vaccaro, Joan A.
Huffman, Fatma G.
author_sort Cheema, Amanpreet K.
collection PubMed
description BACKGROUND: Metabolic outcomes of obesity and its associated disorders may not be equivalent across ethnicity and diabetes status. AIM: In this paper, we examined the association of abdominal obesity, by ethnicity and diabetes status, for indicators of glucose metabolism in Blacks. METHODS: A cross sectional study was conducted in Haitian Americans (n= 186) and African Americans (n= 148) with and without type 2 diabetes mellitus (T2DM). Student’s t-test and Chi-squared test were used to assess differences in mean and proportion values between ethnicities with and without type 2 diabetes mellitus. Relationship between insulin resistance, ethnicity, diabetes status, abdominal obesity, and adiponectin levels were analyzed by analysis of covariance while controlling for confounding variables. RESULTS: Haitian American participants were older (P = .032), had higher fasting plasma glucose (P = .036), and A1C (P = .016), but had lower levels of Hs-CRP (P < .001), insulin and HOMA2-IR and lower abdominal obesity (P = .030), than African Americans. Haitian Americans had significantly lower HOMA2-IR (P = .008) than African Americans when comparing both ethnicities with T2DM, high abdominal obesity, and adiponectin levels lower than the median (<14.75 ng/mL). CONCLUSION: The clinical significance of observed differences in insulin resistance, abdominal obesity, and adiponectin levels between Haitian Americans and African Americans could assist in forming public health policies that are ethnic specific.
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spelling pubmed-68205142019-10-30 Ethnic Differences in Insulin Resistance, Adiponectin Levels and Abdominal Obesity: Haitian Americans and African Americans, with and without Type 2 Diabetes Mellitus Cheema, Amanpreet K. Zarini, Gustavo G. Exebio, Joel Ajabshir, Sahar Shaban, Lemia Antwi, Janet Vaccaro, Joan A. Huffman, Fatma G. Br J Med Med Res Article BACKGROUND: Metabolic outcomes of obesity and its associated disorders may not be equivalent across ethnicity and diabetes status. AIM: In this paper, we examined the association of abdominal obesity, by ethnicity and diabetes status, for indicators of glucose metabolism in Blacks. METHODS: A cross sectional study was conducted in Haitian Americans (n= 186) and African Americans (n= 148) with and without type 2 diabetes mellitus (T2DM). Student’s t-test and Chi-squared test were used to assess differences in mean and proportion values between ethnicities with and without type 2 diabetes mellitus. Relationship between insulin resistance, ethnicity, diabetes status, abdominal obesity, and adiponectin levels were analyzed by analysis of covariance while controlling for confounding variables. RESULTS: Haitian American participants were older (P = .032), had higher fasting plasma glucose (P = .036), and A1C (P = .016), but had lower levels of Hs-CRP (P < .001), insulin and HOMA2-IR and lower abdominal obesity (P = .030), than African Americans. Haitian Americans had significantly lower HOMA2-IR (P = .008) than African Americans when comparing both ethnicities with T2DM, high abdominal obesity, and adiponectin levels lower than the median (<14.75 ng/mL). CONCLUSION: The clinical significance of observed differences in insulin resistance, abdominal obesity, and adiponectin levels between Haitian Americans and African Americans could assist in forming public health policies that are ethnic specific. 2014-06-16 2014-09 /pmc/articles/PMC6820514/ /pubmed/31667161 http://dx.doi.org/10.9734/bjmmr/2014/10333 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Cheema, Amanpreet K.
Zarini, Gustavo G.
Exebio, Joel
Ajabshir, Sahar
Shaban, Lemia
Antwi, Janet
Vaccaro, Joan A.
Huffman, Fatma G.
Ethnic Differences in Insulin Resistance, Adiponectin Levels and Abdominal Obesity: Haitian Americans and African Americans, with and without Type 2 Diabetes Mellitus
title Ethnic Differences in Insulin Resistance, Adiponectin Levels and Abdominal Obesity: Haitian Americans and African Americans, with and without Type 2 Diabetes Mellitus
title_full Ethnic Differences in Insulin Resistance, Adiponectin Levels and Abdominal Obesity: Haitian Americans and African Americans, with and without Type 2 Diabetes Mellitus
title_fullStr Ethnic Differences in Insulin Resistance, Adiponectin Levels and Abdominal Obesity: Haitian Americans and African Americans, with and without Type 2 Diabetes Mellitus
title_full_unstemmed Ethnic Differences in Insulin Resistance, Adiponectin Levels and Abdominal Obesity: Haitian Americans and African Americans, with and without Type 2 Diabetes Mellitus
title_short Ethnic Differences in Insulin Resistance, Adiponectin Levels and Abdominal Obesity: Haitian Americans and African Americans, with and without Type 2 Diabetes Mellitus
title_sort ethnic differences in insulin resistance, adiponectin levels and abdominal obesity: haitian americans and african americans, with and without type 2 diabetes mellitus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820514/
https://www.ncbi.nlm.nih.gov/pubmed/31667161
http://dx.doi.org/10.9734/bjmmr/2014/10333
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