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If we build it they will come: targeting the immune response to breast cancer
Historically, breast cancer tumors have been considered immunologically quiescent, with the majority of tumors demonstrating low lymphocyte infiltration, low mutational burden, and modest objective response rates to anti-PD-1/PD-L1 monotherapy. Tumor and immunologic profiling has shed light on poten...
Autores principales: | Gatti-Mays, Margaret E., Balko, Justin M., Gameiro, Sofia R., Bear, Harry D., Prabhakaran, Sangeetha, Fukui, Jami, Disis, Mary L., Nanda, Rita, Gulley, James L., Kalinsky, Kevin, Abdul Sater, Houssein, Sparano, Joseph A., Cescon, David, Page, David B., McArthur, Heather, Adams, Sylvia, Mittendorf, Elizabeth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820540/ https://www.ncbi.nlm.nih.gov/pubmed/31700993 http://dx.doi.org/10.1038/s41523-019-0133-7 |
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