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Silencing of Neuropilins and GIPC1 in pancreatic ductal adenocarcinoma exerts multiple cellular and molecular antitumor effects

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer mortality, with new treatment options urgently needed. Neuropilins-1/-2 (NRP1, NRP2) are receptors for semaphorins and angiogenic growth factors, while the GAIP interacting protein C-terminus 1 (GIPC1, aka Synectin) interacts with...

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Detalles Bibliográficos
Autores principales:	Borchardt, Hannes, Schulz, Alexander, Datta, Kaustubh, Muders, Michael H., Aigner, Achim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820541/ https://www.ncbi.nlm.nih.gov/pubmed/31664117 http://dx.doi.org/10.1038/s41598-019-51881-8

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