Study of the binding mechanism of aptamer to palytoxin by docking and molecular simulation

This paper provides a feasible model for molecular structure analysis and interaction mechanism of aptamer and micromolecule. In this study, modeling and dynamic simulation of ssDNA aptamer (P-18S2) and target (Palytoxin, PTX) were performed separately. Then, the complex structure between DNA and PT...

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Detalles Bibliográficos
Autores principales: Hu, Bo, Zhou, Rong, Li, Zhengang, Ouyang, Shengqun, Li, Zhen, Hu, Wei, Wang, Lianghua, Jiao, Binghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820544/
https://www.ncbi.nlm.nih.gov/pubmed/31664144
http://dx.doi.org/10.1038/s41598-019-52066-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820544/
https://www.ncbi.nlm.nih.gov/pubmed/31664144
http://dx.doi.org/10.1038/s41598-019-52066-z

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