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Long-term protective efficacy with a BCG-prime ID93/GLA-SE boost regimen against the hyper-virulent Mycobacterium tuberculosis strain K in a mouse model
Since ID93/GLA-SE was developed as a targeted BCG-prime booster vaccine, in the present study, we evaluated the protective efficacy of ID93/GLA-SE as a boost to a BCG-prime against the hypervirulent Mycobacterium tuberculosis (Mtb) K challenge to provide further information on the development and ap...
Autores principales: | Kwon, Kee Woong, Lee, Ara, Larsen, Sasha E., Baldwin, Susan L., Coler, Rhea N., Reed, Steven G., Cho, Sang-Nae, Ha, Sang-Jun, Shin, Sung Jae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820558/ https://www.ncbi.nlm.nih.gov/pubmed/31664157 http://dx.doi.org/10.1038/s41598-019-52146-0 |
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