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Neonatal thrush of newborns: Oral candidiasis?

OBJECTIVES: Neonatal thrush, also called oral candidiasis, is commonly a clinical diagnosis based on white patches on oral mucosal surfaces. Candida albicans is often associated with it. This clinical study aimed to investigate the presence of C. albicans among newborns with or without clinical find...

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Autores principales: Vainionpää, Anne, Tuomi, Jenni, Kantola, Saara, Anttonen, Vuokko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820580/
https://www.ncbi.nlm.nih.gov/pubmed/31687193
http://dx.doi.org/10.1002/cre2.213
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author Vainionpää, Anne
Tuomi, Jenni
Kantola, Saara
Anttonen, Vuokko
author_facet Vainionpää, Anne
Tuomi, Jenni
Kantola, Saara
Anttonen, Vuokko
author_sort Vainionpää, Anne
collection PubMed
description OBJECTIVES: Neonatal thrush, also called oral candidiasis, is commonly a clinical diagnosis based on white patches on oral mucosal surfaces. Candida albicans is often associated with it. This clinical study aimed to investigate the presence of C. albicans among newborns with or without clinical findings of candidiasis on oral mucosa. Another aim was to investigate how thrush responded to current therapy by acidic liquids such as lingonberry or lemon juice. MATERIAL AND METHODS: Swipe samples were collected from 32 healthy, full‐term infants younger than 12 months with or without white patches on oral mucosa. Clinical diagnosis of thrush was made by a community nurse based on thick and yellowish white patches. The routine therapy was oral lingonberry or lemon juice or soda water. Disappearing of patches was controlled by a phone call about 2 weeks after the baseline. Both parents and nurses gave background factors by filling a questionnaire. RESULTS: One (3%) infant without clinical signs was diagnosed with Candida parapsilosis, none with C. albicans. Thrush resembling candidiasis was diagnosed clinically in four (12.5%) children. Three out of four parents reported persisting findings after 2 weeks. Only the maternal mastitis and use of antibiotics were significantly associated with thrush (p = .001). C. albicans was not discovered from babies with clinical thrush. CONCLUSIONS: Aetiology of the white patches remained unclear. The current way of treating them with acidic liquids is not efficient. Additional studies are needed.
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spelling pubmed-68205802019-11-04 Neonatal thrush of newborns: Oral candidiasis? Vainionpää, Anne Tuomi, Jenni Kantola, Saara Anttonen, Vuokko Clin Exp Dent Res Short Communication OBJECTIVES: Neonatal thrush, also called oral candidiasis, is commonly a clinical diagnosis based on white patches on oral mucosal surfaces. Candida albicans is often associated with it. This clinical study aimed to investigate the presence of C. albicans among newborns with or without clinical findings of candidiasis on oral mucosa. Another aim was to investigate how thrush responded to current therapy by acidic liquids such as lingonberry or lemon juice. MATERIAL AND METHODS: Swipe samples were collected from 32 healthy, full‐term infants younger than 12 months with or without white patches on oral mucosa. Clinical diagnosis of thrush was made by a community nurse based on thick and yellowish white patches. The routine therapy was oral lingonberry or lemon juice or soda water. Disappearing of patches was controlled by a phone call about 2 weeks after the baseline. Both parents and nurses gave background factors by filling a questionnaire. RESULTS: One (3%) infant without clinical signs was diagnosed with Candida parapsilosis, none with C. albicans. Thrush resembling candidiasis was diagnosed clinically in four (12.5%) children. Three out of four parents reported persisting findings after 2 weeks. Only the maternal mastitis and use of antibiotics were significantly associated with thrush (p = .001). C. albicans was not discovered from babies with clinical thrush. CONCLUSIONS: Aetiology of the white patches remained unclear. The current way of treating them with acidic liquids is not efficient. Additional studies are needed. John Wiley and Sons Inc. 2019-07-21 /pmc/articles/PMC6820580/ /pubmed/31687193 http://dx.doi.org/10.1002/cre2.213 Text en ©2019 The Authors. Clinical and Experimental Dental Research published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Vainionpää, Anne
Tuomi, Jenni
Kantola, Saara
Anttonen, Vuokko
Neonatal thrush of newborns: Oral candidiasis?
title Neonatal thrush of newborns: Oral candidiasis?
title_full Neonatal thrush of newborns: Oral candidiasis?
title_fullStr Neonatal thrush of newborns: Oral candidiasis?
title_full_unstemmed Neonatal thrush of newborns: Oral candidiasis?
title_short Neonatal thrush of newborns: Oral candidiasis?
title_sort neonatal thrush of newborns: oral candidiasis?
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820580/
https://www.ncbi.nlm.nih.gov/pubmed/31687193
http://dx.doi.org/10.1002/cre2.213
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