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Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores

Nanopore sensing is a powerful single-molecule approach for the detection of biomolecules. Recent studies have demonstrated that aerolysin is a promising candidate to improve the accuracy of DNA sequencing and to develop novel single-molecule proteomic strategies. However, the structure–function rel...

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Detalles Bibliográficos
Autores principales: Cao, Chan, Cirauqui, Nuria, Marcaida, Maria Jose, Buglakova, Elena, Duperrex, Alice, Radenovic, Aleksandra, Dal Peraro, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820719/
https://www.ncbi.nlm.nih.gov/pubmed/31664022
http://dx.doi.org/10.1038/s41467-019-12690-9