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FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons
Several FRET (fluorescence resonance energy transfer)-based biosensors for intracellular detection of cyclic nucleotides have been designed in the past decade. However, few such biosensors are available for cGMP, and even fewer that detect low nanomolar cGMP concentrations. Our aim was to develop a...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820734/ https://www.ncbi.nlm.nih.gov/pubmed/31701023 http://dx.doi.org/10.1038/s42003-019-0641-x |