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FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons

Several FRET (fluorescence resonance energy transfer)-based biosensors for intracellular detection of cyclic nucleotides have been designed in the past decade. However, few such biosensors are available for cGMP, and even fewer that detect low nanomolar cGMP concentrations. Our aim was to develop a...

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Detalles Bibliográficos
Autores principales: Calamera, Gaia, Li, Dan, Ulsund, Andrea Hembre, Kim, Jeong Joo, Neely, Oliver C., Moltzau, Lise Román, Bjørnerem, Marianne, Paterson, David, Kim, Choel, Levy, Finn Olav, Andressen, Kjetil Wessel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820734/
https://www.ncbi.nlm.nih.gov/pubmed/31701023
http://dx.doi.org/10.1038/s42003-019-0641-x