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Herbal components of Japanese Kampo medicines exert laxative actions in colonic epithelium cells via activation of BK and CFTR channels

Japanese Kampo medicines Junchoto and Mashiningan are mixtures of numerous herbal plant extracts and empirically known to exert laxative actions by stimulating fluid secretion in the colonic epithelium. However, it is unknown which and how the herbal components of these crude Kampo drugs are effecti...

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Detalles Bibliográficos
Autores principales: Numata, Tomohiro, Sato-Numata, Kaori, Okada, Yasunobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820752/
https://www.ncbi.nlm.nih.gov/pubmed/31664151
http://dx.doi.org/10.1038/s41598-019-52171-z