Chloroquine modulates inflammatory autoimmune responses through Nurr1 in autoimmune diseases

For over a half-century the anti-malarial drug chloroquine (CQ) has been used as a therapeutic agent, alone or in combination, to treat autoimmune diseases. However, neither the underlying mechanism(s) of action nor their molecular target(s) are well defined. The orphan nuclear receptor Nurr1 (also...

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Detalles Bibliográficos
Autores principales: Park, Tae-Yoon, Jang, Yongwoo, Kim, Woori, Shin, Joon, Toh, Hui Ting, Kim, Chun-Hyung, Yoon, Ho Sup, Leblanc, Pierre, Kim, Kwang-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820774/
https://www.ncbi.nlm.nih.gov/pubmed/31664129
http://dx.doi.org/10.1038/s41598-019-52085-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820774/
https://www.ncbi.nlm.nih.gov/pubmed/31664129
http://dx.doi.org/10.1038/s41598-019-52085-w

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