Leucine-rich diet induces a shift in tumour metabolism from glycolytic towards oxidative phosphorylation, reducing glucose consumption and metastasis in Walker-256 tumour-bearing rats

Leucine can stimulate protein synthesis in skeletal muscle, and recent studies have shown an increase in leucine-related mitochondrial biogenesis and oxidative phosphorylation capacity in muscle cells. However, leucine-related effects in tumour tissues are still poorly understood. Thus, we described...

Descripción completa

Detalles Bibliográficos
Autores principales: Viana, Laís Rosa, Tobar, Natália, Busanello, Estela Natacha Brandt, Marques, Ana Carolina, de Oliveira, Andre Gustavo, Lima, Tanes I., Machado, Gabrielly, Castelucci, Bianca Gazieri, Ramos, Celso Dario, Brunetto, Sérgio Q, Silveira, Leonardo Reis, Vercesi, Anibal Eugenio, Consonni, Sílvio Roberto, Gomes-Marcondes, Maria Cristina Cintra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820796/
https://www.ncbi.nlm.nih.gov/pubmed/31664147
http://dx.doi.org/10.1038/s41598-019-52112-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820796/
https://www.ncbi.nlm.nih.gov/pubmed/31664147
http://dx.doi.org/10.1038/s41598-019-52112-w

Ejemplares similares