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A 96-multiplex capillary electrophoresis screening platform for product based evolution of P450 BM3
The main challenge that prevents a broader application of directed enzyme evolution is the lack of high-throughput screening systems with universal product analytics. Most directed evolution campaigns employ screening systems based on colorimetric or fluorogenic surrogate substrates or universal qua...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820799/ https://www.ncbi.nlm.nih.gov/pubmed/31664146 http://dx.doi.org/10.1038/s41598-019-52077-w |