Cargando…
Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue
The formation of Aβ amyloid fibrils is a neuropathological hallmark of Alzheimer’s disease and cerebral amyloid angiopathy. However, the structure of Aβ amyloid fibrils from brain tissue is poorly understood. Here we report the purification of Aβ amyloid fibrils from meningeal Alzheimer’s brain tiss...
Autores principales: | Kollmer, Marius, Close, William, Funk, Leonie, Rasmussen, Jay, Bsoul, Aref, Schierhorn, Angelika, Schmidt, Matthias, Sigurdson, Christina J., Jucker, Mathias, Fändrich, Marcus |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820800/ https://www.ncbi.nlm.nih.gov/pubmed/31664019 http://dx.doi.org/10.1038/s41467-019-12683-8 |
Ejemplares similares
-
Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids
por: Liberta, Falk, et al.
Publicado: (2019) -
Cryo-EM structure of a catalytic amyloid fibril
por: Heerde, Thomas, et al.
Publicado: (2023) -
Cryo-EM structure and polymorphic maturation of a viral transduction enhancing amyloid fibril
por: Heerde, Thomas, et al.
Publicado: (2023) -
Amyloid plaque structure and cell surface interactions of β-amyloid fibrils revealed by electron tomography
por: Han, Shen, et al.
Publicado: (2017) -
Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding
por: Heerde, Thomas, et al.
Publicado: (2022)