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Variation of PEAR1 DNA methylation influences platelet and leukocyte function

BACKGROUND: Platelet-endothelial aggregation receptor 1 (PEAR-1) is a transmembrane receptor involved in platelet activation and megakaryopoiesis whose expression is driven by DNA methylation. PEAR1 variants were associated with differential platelet response to activation and cardiovascular outcome...

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Detalles Bibliográficos
Autores principales:	Izzi, Benedetta, Gianfagna, Francesco, Yang, Wen-Yi, Cludts, Katrien, De Curtis, Amalia, Verhamme, Peter, Di Castelnuovo, Augusto, Cerletti, Chiara, Donati, Maria Benedetta, de Gaetano, Giovanni, Staessen, Jan A., Hoylaerts, Marc F., Iacoviello, Licia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820903/ https://www.ncbi.nlm.nih.gov/pubmed/31665082 http://dx.doi.org/10.1186/s13148-019-0744-8

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