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DNA methylation in repeat negative prostate biopsies as a marker of missed prostate cancer

BACKGROUND: Men often undergo repeat prostate biopsies because of suspicion of missed cancer. We assessed if (i) methylation of selected genes in prostate tissue vary with aging and (ii) methylation alterations in repeat biopsies predict missed prostate cancer. METHODS: We conducted a case-control s...

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Detalles Bibliográficos
Autores principales: Fiano, Valentina, Zugna, Daniela, Grasso, Chiara, Trevisan, Morena, Delsedime, Luisa, Molinaro, Luca, Cassoni, Paola, Papotti, Mauro, Merletti, Franco, Akre, Olof, Pettersson, Andreas, De Marco, Laura, Richiardi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820908/
https://www.ncbi.nlm.nih.gov/pubmed/31666119
http://dx.doi.org/10.1186/s13148-019-0746-6