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Matrisome analysis of intrahepatic cholangiocarcinoma unveils a peculiar cancer-associated extracellular matrix structure

BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) is a malignancy that arises from the intrahepatic biliary tree, showing high mortality rates due to its late clinical presentation and limited treatment options. iCCA is characterized by a dense, reactive desmoplastic stroma marked by a dramatic acc...

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Detalles Bibliográficos
Autores principales: Carpino, Guido, Overi, Diletta, Melandro, Fabio, Grimaldi, Alessio, Cardinale, Vincenzo, Di Matteo, Sabina, Mennini, Gianluca, Rossi, Massimo, Alvaro, Domenico, Barnaba, Vincenzo, Gaudio, Eugenio, Mancone, Carmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821022/
https://www.ncbi.nlm.nih.gov/pubmed/31687002
http://dx.doi.org/10.1186/s12014-019-9257-x