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Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium

BACKGROUND: Genetics play an important role in intracranial aneurysm (IA) pathophysiology. Genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) that are linked to IA but how they affect disease pathobiology remains poorly understood. We used Encyclopedia of...

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Detalles Bibliográficos
Autores principales:	Poppenberg, Kerry E., Jiang, Kaiyu, Tso, Michael K., Snyder, Kenneth V., Siddiqui, Adnan H., Kolega, John, Jarvis, James N., Meng, Hui, Tutino, Vincent M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821037/ https://www.ncbi.nlm.nih.gov/pubmed/31666072 http://dx.doi.org/10.1186/s12920-019-0591-7

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