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A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing
Insufficient and delayed fracture healing remain significant public health problems with limited therapeutic options. Phosphoinositide 3-kinase (PI3K) signaling, a major pathway involved in regulation of fracture healing, promotes proliferation, migration, and differentiation of osteoprogenitors. We...
Autores principales: | Doherty, Laura, Yu, Jungeun, Wang, Xi, Hankenson, Kurt D., Kalajzic, Ivo, Sanjay, Archana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821073/ https://www.ncbi.nlm.nih.gov/pubmed/31665177 http://dx.doi.org/10.1371/journal.pone.0223846 |
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