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A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury
The principles of Refinement, Replacement and Reduction (3R’s) should be taken into account when animals must be used for scientific purpose. Here, a Reduction / Refinement approach was applied to the procedure of spinal cord injury (SCI), an animal model used in rehabilitation medicine research, in...
Autores principales: | Redaelli, Veronica, Papa, Simonetta, Marsella, Gerardo, Grignaschi, Giuliano, Bosi, Alice, Ludwig, Nicola, Luzi, Fabio, Vismara, Irma, Rimondo, Stefano, Veglianese, Pietro, Tepteva, Svetlana, Mazzola, Silvia, Zerbi, Pietro, Porcu, Luca, Roughan, John V., Parati, Gianfranco, Calvillo, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821094/ https://www.ncbi.nlm.nih.gov/pubmed/31665157 http://dx.doi.org/10.1371/journal.pone.0224337 |
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