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mTOR-regulated U2af1 tandem exon splicing specifies transcriptome features for translational control

U2 auxiliary factor 1 (U2AF1) functions in 3′-splice site selection during pre-mRNA processing. Alternative usage of duplicated tandem exons in U2AF1 produces two isoforms, U2AF1a and U2AF1b, but their functional differences are unappreciated due to their homology. Through integrative approaches of...

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Detalles Bibliográficos
Autores principales: Chang, Jae-Woong, Yeh, Hsin-Sung, Park, Meeyeon, Erber, Luke, Sun, Jiao, Cheng, Sze, Bui, Alexander M, Fahmi, Naima Ahmed, Nasti, Ryan, Kuang, Rui, Chen, Yue, Zhang, Wei, Yong, Jeongsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821156/
https://www.ncbi.nlm.nih.gov/pubmed/31504847
http://dx.doi.org/10.1093/nar/gkz761