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Functional analysis of Cwc24 ZF-domain in 5′ splice site selection

The essential splicing factor Cwc24 contains a zinc-finger (ZF) domain required for its function in splicing. Cwc24 binds over the 5′ splice site after the spliceosome is activated, and its binding prior to Prp2-mediated spliceosome remodeling is important for proper interactions of U5 and U6 with t...

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Detalles Bibliográficos
Autores principales:	Wu, Nan-Ying, Cheng, Soo-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821175/ https://www.ncbi.nlm.nih.gov/pubmed/31504764 http://dx.doi.org/10.1093/nar/gkz733

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