The human Shu complex functions with PDS5B and SPIDR to promote homologous recombination

RAD51 plays a central role in homologous recombination during double-strand break repair and in replication fork dynamics. Misregulation of RAD51 is associated with genetic instability and cancer. RAD51 is regulated by many accessory proteins including the highly conserved Shu complex. Here, we repo...

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Detalles Bibliográficos
Autores principales: Martino, Julieta, Brunette, Gregory J, Barroso-González, Jonathan, Moiseeva, Tatiana N, Smith, Chelsea M, Bakkenist, Christopher J, O’Sullivan, Roderick J, Bernstein, Kara A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821187/
https://www.ncbi.nlm.nih.gov/pubmed/31665741
http://dx.doi.org/10.1093/nar/gkz738

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