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Human mitochondrial DNA is extensively methylated in a non-CpG context

Mitochondrial dysfunction plays critical roles in cancer development and related therapeutic response; however, exact molecular mechanisms remain unclear. Recently, alongside the discovery of mitochondrial-specific DNA methyltransferases, global and site-specific methylation of the mitochondrial gen...

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Detalles Bibliográficos
Autores principales: Patil, Vibha, Cuenin, Cyrille, Chung, Felicia, Aguilera, Jesus R Rodriguez, Fernandez-Jimenez, Nora, Romero-Garmendia, Irati, Bilbao, Jose Ramon, Cahais, Vincent, Rothwell, Joseph, Herceg, Zdenko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821263/
https://www.ncbi.nlm.nih.gov/pubmed/31665742
http://dx.doi.org/10.1093/nar/gkz762