Ash2l interacts with Oct4-stemness circuitry to promote super-enhancer-driven pluripotency network

Pluripotency and cell fates can be modulated through the regulation of super-enhancers; however, the underlying mechanisms are unclear. Here, we showed a novel mechanism in which Ash2l directly binds to super-enhancers of several stemness genes to regulate pluripotency and self-renewal in pluripoten...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Ping-Hsing, Chien, Yueh, Wang, Mong-Lien, Hsu, Chih-Hung, Laurent, Benoit, Chou, Shih-Jie, Chang, Wei-Chao, Chien, Chian-Shiu, Li, Hsin-Yang, Lee, Hsin-Chen, Huo, Teh-Ia, Hung, Jui-Hung, Chen, Chung-Hsuan, Chiou, Shih-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821267/
https://www.ncbi.nlm.nih.gov/pubmed/31555818
http://dx.doi.org/10.1093/nar/gkz801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821267/
https://www.ncbi.nlm.nih.gov/pubmed/31555818
http://dx.doi.org/10.1093/nar/gkz801

Ejemplares similares