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Ash2l interacts with Oct4-stemness circuitry to promote super-enhancer-driven pluripotency network

Pluripotency and cell fates can be modulated through the regulation of super-enhancers; however, the underlying mechanisms are unclear. Here, we showed a novel mechanism in which Ash2l directly binds to super-enhancers of several stemness genes to regulate pluripotency and self-renewal in pluripoten...

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Detalles Bibliográficos
Autores principales:	Tsai, Ping-Hsing, Chien, Yueh, Wang, Mong-Lien, Hsu, Chih-Hung, Laurent, Benoit, Chou, Shih-Jie, Chang, Wei-Chao, Chien, Chian-Shiu, Li, Hsin-Yang, Lee, Hsin-Chen, Huo, Teh-Ia, Hung, Jui-Hung, Chen, Chung-Hsuan, Chiou, Shih-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821267/ https://www.ncbi.nlm.nih.gov/pubmed/31555818 http://dx.doi.org/10.1093/nar/gkz801

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