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DNA Analysis by Restriction Enzyme (DARE) enables concurrent genomic and epigenomic characterization of single cells

Genome-wide profiling of copy number alterations and DNA methylation in single cells could enable detailed investigation into the genomic and epigenomic heterogeneity of complex cell populations. However, current methods to do this require complex sample processing and cleanup steps, lack consistenc...

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Detalles Bibliográficos
Autores principales:	Viswanathan, Ramya, Cheruba, Elsie, Cheow, Lih Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821369/ https://www.ncbi.nlm.nih.gov/pubmed/31418018 http://dx.doi.org/10.1093/nar/gkz717

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