Cargando…

HiCNN: a very deep convolutional neural network to better enhance the resolution of Hi-C data

MOTIVATION: High-resolution Hi-C data are indispensable for the studies of three-dimensional (3D) genome organization at kilobase level. However, generating high-resolution Hi-C data (e.g. 5 kb) by conducting Hi-C experiments needs millions of mammalian cells, which may eventually generate billions...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Tong, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821373/
https://www.ncbi.nlm.nih.gov/pubmed/31056636
http://dx.doi.org/10.1093/bioinformatics/btz251