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Recovery of TRIM25-Mediated RIG-I Ubiquitination through Suppression of NS1 by RNA Aptamers

Non-structural protein 1 (NS1) of influenza virus has been shown to inhibit the innate immune response by blocking the induction of interferon (IFN). In this study, we isolated two single-stranded RNA aptamers specific to NS1 with K(d) values of 1.62 ± 0.30 nM and 1.97 ± 0.27 nM, respectively, using...

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Detalles Bibliográficos
Autores principales:	Woo, Hye-Min, Lee, Jin-Moo, Kim, Chul-Joong, Lee, Jong-Soo, Jeong, Yong-Joo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821451/ https://www.ncbi.nlm.nih.gov/pubmed/31600868 http://dx.doi.org/10.14348/molcells.2019.0157

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