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INTIMA-MEDIA THICKNESS OF THE CAROTID ARTERIES IS AFFECTED BY PUBERTAL MATURATION IN HEALTHY ADOLESCENTS
OBJECTIVE: To contribute to the assessment of normal parameters of carotid intima-media thickness (CIMT) in healthy adolescents. METHODS: A cross-sectional study was conducted through clinical, laboratory and ultrasound evaluation in 61 healthy adolescents. The inclusion criteria consisted of being...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade de Pediatria de São Paulo
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821474/ https://www.ncbi.nlm.nih.gov/pubmed/31291443 http://dx.doi.org/10.1590/1984-0462/;2019;37;4;00010 |
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author | Zanini, Jovita Lane Soares Santos Rodrigues, Tânia Maria Barreto Barra, Cristina Botelho Filgueiras, Maria Francisca Tereza Freire Silva, Ivani Novato |
author_facet | Zanini, Jovita Lane Soares Santos Rodrigues, Tânia Maria Barreto Barra, Cristina Botelho Filgueiras, Maria Francisca Tereza Freire Silva, Ivani Novato |
author_sort | Zanini, Jovita Lane Soares Santos |
collection | PubMed |
description | OBJECTIVE: To contribute to the assessment of normal parameters of carotid intima-media thickness (CIMT) in healthy adolescents. METHODS: A cross-sectional study was conducted through clinical, laboratory and ultrasound evaluation in 61 healthy adolescents. The inclusion criteria consisted of being in good health. The exclusion criteria were: presence or history of any chronic disease; being obese or overweight according to the World Health Organization (WHO) established criterion; continuous use of medication; or presenting a febrile condition or requiring medication within 48-hours prior to assessment. The pubertal stages were evaluated using the Tanner criteria. The high-resolution B-mode ultrasound examinations were performed according to the recommendations of the Consensus Statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. RESULTS: Adolescents were 14±2.6 years old, 62.3% female, 19 (31%) at early puberty (Tanner II and III), and 38 (62%) at late puberty (Tanner IV and V). They presented normal clinical and laboratorial parameters. CIMT values were 0.46±0.04 to 0.55±0.04 mm on the right and 0.48±0.02 to 0.53±0.04 mm on the left, according to pubertal maturation. CIMT values increased significantly on the right and left sides, according to pubertal stage (p<0.001 and p=0.016), and maximum internal diameters of the common carotid artery (p<0.025 and p<0.003). It was higher in males compared to females. CONCLUSIONS: An increase in CIMT in the healthy adolescents group, according to both age, and the degree of pubertal maturation should be considered when evaluating adolescents in diagnostic procedures. |
format | Online Article Text |
id | pubmed-6821474 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Sociedade de Pediatria de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-68214742019-11-05 INTIMA-MEDIA THICKNESS OF THE CAROTID ARTERIES IS AFFECTED BY PUBERTAL MATURATION IN HEALTHY ADOLESCENTS Zanini, Jovita Lane Soares Santos Rodrigues, Tânia Maria Barreto Barra, Cristina Botelho Filgueiras, Maria Francisca Tereza Freire Silva, Ivani Novato Rev Paul Pediatr Original Article OBJECTIVE: To contribute to the assessment of normal parameters of carotid intima-media thickness (CIMT) in healthy adolescents. METHODS: A cross-sectional study was conducted through clinical, laboratory and ultrasound evaluation in 61 healthy adolescents. The inclusion criteria consisted of being in good health. The exclusion criteria were: presence or history of any chronic disease; being obese or overweight according to the World Health Organization (WHO) established criterion; continuous use of medication; or presenting a febrile condition or requiring medication within 48-hours prior to assessment. The pubertal stages were evaluated using the Tanner criteria. The high-resolution B-mode ultrasound examinations were performed according to the recommendations of the Consensus Statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. RESULTS: Adolescents were 14±2.6 years old, 62.3% female, 19 (31%) at early puberty (Tanner II and III), and 38 (62%) at late puberty (Tanner IV and V). They presented normal clinical and laboratorial parameters. CIMT values were 0.46±0.04 to 0.55±0.04 mm on the right and 0.48±0.02 to 0.53±0.04 mm on the left, according to pubertal maturation. CIMT values increased significantly on the right and left sides, according to pubertal stage (p<0.001 and p=0.016), and maximum internal diameters of the common carotid artery (p<0.025 and p<0.003). It was higher in males compared to females. CONCLUSIONS: An increase in CIMT in the healthy adolescents group, according to both age, and the degree of pubertal maturation should be considered when evaluating adolescents in diagnostic procedures. Sociedade de Pediatria de São Paulo 2019-07-04 /pmc/articles/PMC6821474/ /pubmed/31291443 http://dx.doi.org/10.1590/1984-0462/;2019;37;4;00010 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Original Article Zanini, Jovita Lane Soares Santos Rodrigues, Tânia Maria Barreto Barra, Cristina Botelho Filgueiras, Maria Francisca Tereza Freire Silva, Ivani Novato INTIMA-MEDIA THICKNESS OF THE CAROTID ARTERIES IS AFFECTED BY PUBERTAL MATURATION IN HEALTHY ADOLESCENTS |
title | INTIMA-MEDIA THICKNESS OF THE CAROTID ARTERIES IS AFFECTED BY
PUBERTAL MATURATION IN HEALTHY ADOLESCENTS |
title_full | INTIMA-MEDIA THICKNESS OF THE CAROTID ARTERIES IS AFFECTED BY
PUBERTAL MATURATION IN HEALTHY ADOLESCENTS |
title_fullStr | INTIMA-MEDIA THICKNESS OF THE CAROTID ARTERIES IS AFFECTED BY
PUBERTAL MATURATION IN HEALTHY ADOLESCENTS |
title_full_unstemmed | INTIMA-MEDIA THICKNESS OF THE CAROTID ARTERIES IS AFFECTED BY
PUBERTAL MATURATION IN HEALTHY ADOLESCENTS |
title_short | INTIMA-MEDIA THICKNESS OF THE CAROTID ARTERIES IS AFFECTED BY
PUBERTAL MATURATION IN HEALTHY ADOLESCENTS |
title_sort | intima-media thickness of the carotid arteries is affected by
pubertal maturation in healthy adolescents |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821474/ https://www.ncbi.nlm.nih.gov/pubmed/31291443 http://dx.doi.org/10.1590/1984-0462/;2019;37;4;00010 |
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