AST-120, an Oral Carbon Absorbent, Protects against the Progression of Atherosclerosis in a Mouse Chronic Renal Failure Model by Preserving sFlt-1 Expression Levels

Soluble Flt-1 (sFlt-1), an endogenous antagonist of the proatherogenic cytokine placental growth factor, is decreased in chronic kidney disease (CKD), leading to atherosclerotic progression. In this study, we investigated the effect of AST-120, an oral carbon adsorbent which can remove uremic toxins...

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Detalles Bibliográficos
Autores principales: Nakada, Yasuki, Onoue, Kenji, Nakano, Tomoya, Ishihara, Satomi, Kumazawa, Takuya, Nakagawa, Hitoshi, Ueda, Tomoya, Nishida, Taku, Soeda, Tsunenari, Okayama, Satoshi, Watanabe, Makoto, Kawakami, Rika, Saito, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821698/
https://www.ncbi.nlm.nih.gov/pubmed/31666542
http://dx.doi.org/10.1038/s41598-019-51292-9

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