Pan-Cancer Analysis Reveals Disrupted Circadian Clock Associates With T Cell Exhaustion

Although dysfunctional circadian clock has emerged as a hallmark of cancer, fundamental gaps remain in our understanding of the underlying mechanisms involved. Here, we systematically analyze the core genes of the circadian clock (CLOCK, ARNTL, ARNTL2, NPAS2, NR1D1, NR1D2, CRY1, CRY2, RORA, RORB, RO...

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Detalles Bibliográficos
Autores principales: Wu, Yingcheng, Tao, Baorui, Zhang, Tianyang, Fan, Yihui, Mao, Renfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821711/
https://www.ncbi.nlm.nih.gov/pubmed/31708917
http://dx.doi.org/10.3389/fimmu.2019.02451

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