Cigarette smoke affects the onco-suppressor DAB2IP expression in bronchial epithelial cells of COPD patients

Cigarette smoke is a risk factor for COPD and lung cancer. In cancer, epigenetic modifications affect the expression of Enhancer of Zester Homolog 2 (EZH2), and silenced disabled homolog 2 interacting protein gene (DAB2IP) (onco-suppressor gene) by Histone H3 tri-methylation in lysine 27 (H3K27me3)....

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Detalles Bibliográficos
Autores principales: Anzalone, Giulia, Arcoleo, Giuseppe, Bucchieri, Fabio, Montalbano, Angela M., Marchese, Roberto, Albano, Giusy D., Di Sano, Caterina, Moscato, Monica, Gagliardo, Rosalia, Ricciardolo, Fabio L. M., Profita, Mirella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821751/
https://www.ncbi.nlm.nih.gov/pubmed/31666665
http://dx.doi.org/10.1038/s41598-019-52179-5

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