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Phase I Trial of Pyragrel, a Novel Thromboxane Synthetase Inhibitor, to Evaluate the Safety, Tolerability, and Pharmacokinetics in Healthy Volunteers

Background and Objective: Inhibition of thrombosis and platelet aggregation through a thromboxane synthetase inhibitor proved to be an effective and promising treatment for cardiovascular and/or cerebrovascular disease (CCVD) patients. This phase I study evaluated the safety, tolerability, and pharm...

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Detalles Bibliográficos
Autores principales:	Zou, Chan, Zuo, Xiaocong, Huang, Jie, Hua, Ye, Yang, Shuang, Yang, Xiaoyan, Guo, Can, Tan, Hongyi, Chen, Jun, Chu, Zhaoxing, Pei, Qi, Yang, Guoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821791/ https://www.ncbi.nlm.nih.gov/pubmed/31708774 http://dx.doi.org/10.3389/fphar.2019.01231

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