Targeted deletion of NFAT-Interacting-Protein-(NIP) 45 resolves experimental asthma by inhibiting Innate Lymphoid Cells group 2 (ILC2)

Here we investigated the role of NFAT-interacting protein (NIP)-45, an Interleukin (IL)-4 inducing Transcription Factor, and its impact on the differentiation of Group 2 Innate -Lymphoid -Cells (ILC2s) in the pathogenesis of asthma. NIP45, a transcription factor regulating NFATc1 activity, mRNA was...

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Detalles Bibliográficos
Autores principales: Koch, Sonja, Knipfer, Lisa, Kölle, Julia, Mirzakhani, Hooman, Graser, Anna, Zimmermann, Theodor, Kiefer, Alexander, Melichar, Volker O., Rascher, Wolfgang, Papadopoulos, Nikolaos G., Rieker, Ralf J., Raby, Benjamin A., Weiss, Scott T., Wirtz, Stefan, Finotto, Susetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821848/
https://www.ncbi.nlm.nih.gov/pubmed/31666531
http://dx.doi.org/10.1038/s41598-019-51690-z

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