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Dissecting the evolvability landscape of the CalB active site toward aromatic substrates
A key event in the directed evolution of enzymes is the systematic use of mutagenesis and selection, a process that can give rise to mutant libraries containing millions of protein variants. To this day, the functional analysis and identification of active variants among such high numbers of mutatio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821916/ https://www.ncbi.nlm.nih.gov/pubmed/31666622 http://dx.doi.org/10.1038/s41598-019-51940-0 |