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Transgenic mouse models expressing human and macaque prion protein exhibit similar prion susceptibility on a strain-dependent manner
Cynomolgus macaque has been used for the evaluation of the zoonotic potential of prion diseases, especially for classical-Bovine Spongiform Encephalopathy (classical-BSE) infectious agent. PrP amino acid sequence is considered to play a key role in the susceptibility to prion strains and only one am...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821920/ https://www.ncbi.nlm.nih.gov/pubmed/31666632 http://dx.doi.org/10.1038/s41598-019-52155-z |