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Unraveling the Role of Silent Mutation in the ω-Subunit of Escherichia coli RNA Polymerase: Structure Transition Inhibits Transcription
[Image: see text] The bacterial RNA polymerase is a multi-subunit enzyme complex composed of six subunits, α(2)ββ’σω. The function of this enzyme is to transcribe the DNA base sequence to the RNA intermediate, which is ultimately translated to protein. Though the contribution of each subunit in RNA...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822122/ https://www.ncbi.nlm.nih.gov/pubmed/31681877 http://dx.doi.org/10.1021/acsomega.9b02103 |