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(R)-Ketamine Rapidly Ameliorates the Decreased Spine Density in the Medial Prefrontal Cortex and Hippocampus of Susceptible Mice After Chronic Social Defeat Stress

BACKGROUND: A recent study demonstrated that spine formation rates by ketamine in the prefrontal cortex (PFC) were not altered at 3–6 h following a single injection, but were markedly altered at 12–24 h. Here, we investigated the acute (3 h post-treatment) effects of (R)-ketamine in the decreased sp...

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Detalles Bibliográficos
Autores principales: Zhang, Jiancheng, Qu, Youge, Chang, Lijia, Pu, Yaoyu, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822137/
https://www.ncbi.nlm.nih.gov/pubmed/31504547
http://dx.doi.org/10.1093/ijnp/pyz048

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