Widespread Changes in Positive Allosteric Modulation of the Muscarinic M(1) Receptor in Some Participants With Schizophrenia

BACKGROUND: Preclinical and some human data suggest allosteric modulation of the muscarinic M(1) receptor (CHRM1) is a promising approach for the treatment of schizophrenia. However, it is suggested there is a subgroup of participants with schizophrenia who have profound loss of cortical CHRM1 (MRDS...

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Detalles Bibliográficos
Autores principales: Hopper, Shaun, Pavey, Geoffrey Mark, Gogos, Andrea, Dean, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822142/
https://www.ncbi.nlm.nih.gov/pubmed/31428788
http://dx.doi.org/10.1093/ijnp/pyz045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822142/
https://www.ncbi.nlm.nih.gov/pubmed/31428788
http://dx.doi.org/10.1093/ijnp/pyz045

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