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Widespread Changes in Positive Allosteric Modulation of the Muscarinic M(1) Receptor in Some Participants With Schizophrenia
BACKGROUND: Preclinical and some human data suggest allosteric modulation of the muscarinic M(1) receptor (CHRM1) is a promising approach for the treatment of schizophrenia. However, it is suggested there is a subgroup of participants with schizophrenia who have profound loss of cortical CHRM1 (MRDS...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822142/ https://www.ncbi.nlm.nih.gov/pubmed/31428788 http://dx.doi.org/10.1093/ijnp/pyz045 |