Cargando…
Targeted Activation of Cystic Fibrosis Transmembrane Conductance Regulator
Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. The majority of CFTR mutations result in impaired chloride channel function as only a fraction of the mutated CFTR reaches the plasma membrane. The development of a therapeutic approach that facili...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822231/ https://www.ncbi.nlm.nih.gov/pubmed/31383454 http://dx.doi.org/10.1016/j.ymthe.2019.07.002 |