Targeted Activation of Cystic Fibrosis Transmembrane Conductance Regulator

Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. The majority of CFTR mutations result in impaired chloride channel function as only a fraction of the mutated CFTR reaches the plasma membrane. The development of a therapeutic approach that facili...

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Detalles Bibliográficos
Autores principales: Villamizar, Olga, Waters, Shafagh A., Scott, Tristan, Saayman, Sheena, Grepo, Nicole, Urak, Ryan, Davis, Alicia, Jaffe, Adam, Morris, Kevin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822231/
https://www.ncbi.nlm.nih.gov/pubmed/31383454
http://dx.doi.org/10.1016/j.ymthe.2019.07.002

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