Cargando…
Biochemical pathways mediated by KLK6 protease in breast cancer
Kallikrein‐related peptidase 6 (KLK6) is a serine protease normally expressed in mammary tissue and aberrantly regulated in breast cancer. At physiological levels, KLK6 functions as a suppressor of breast cancer, while its aberrant overexpression (> 50‐fold higher than normal) is characteristic o...
Autores principales: | Pampalakis, Georgios, Zingkou, Eleni, Sidiropoulos, Konstantinos Gus, Diamandis, Eleftherios P., Zoumpourlis, Vassilis, Yousef, George M., Sotiropoulou, Georgia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822253/ https://www.ncbi.nlm.nih.gov/pubmed/30980596 http://dx.doi.org/10.1002/1878-0261.12493 |
Ejemplares similares
-
Novel specific activity-based probes validate KLK proteases as druggable targets
por: Sotiropoulou, Georgia, et al.
Publicado: (2022) -
The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway
por: Pampalakis, Georgios, et al.
Publicado: (2013) -
Activity-Based Probes for Proteases Pave the Way to Theranostic Applications
por: Sotiropoulou, Georgia, et al.
Publicado: (2022) -
Kallikreins emerge as new regulators of viral infections
por: Pampalakis, Georgios, et al.
Publicado: (2021) -
Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6
por: Sotiropoulou, Georgia, et al.
Publicado: (2012)