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Targeted High Resolution LC/MS(3) Adductomics Method for the Characterization of Endogenous DNA Damage

DNA can be damaged through covalent modifications of the nucleobases by endogenous processes. These modifications, commonly referred to as DNA adducts, can persist and may lead to mutations, and ultimately to the initiation of cancer. A screening methodology for the majority of known endogenous DNA...

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Detalles Bibliográficos
Autores principales: Carrà, Andrea, Guidolin, Valeria, Dator, Romel P., Upadhyaya, Pramod, Kassie, Fekadu, Villalta, Peter W., Balbo, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822301/
https://www.ncbi.nlm.nih.gov/pubmed/31709223
http://dx.doi.org/10.3389/fchem.2019.00658