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Targeted High Resolution LC/MS(3) Adductomics Method for the Characterization of Endogenous DNA Damage
DNA can be damaged through covalent modifications of the nucleobases by endogenous processes. These modifications, commonly referred to as DNA adducts, can persist and may lead to mutations, and ultimately to the initiation of cancer. A screening methodology for the majority of known endogenous DNA...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822301/ https://www.ncbi.nlm.nih.gov/pubmed/31709223 http://dx.doi.org/10.3389/fchem.2019.00658 |