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Hypermethylation of mismatch repair gene hMSH2 associates with platinum-resistant disease in epithelial ovarian cancer

PURPOSE: One major reason of the high mortality of epithelial ovarian cancer (EOC) is due to platinum-based chemotherapy resistance. Aberrant DNA methylation may be a potential mechanism underlying the development of platinum resistance in EOC. The purpose of this study is to discover potential aber...

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Detalles Bibliográficos
Autores principales:	Tian, Hua, Yan, Li, Xiao-fei, Li, Hai-yan, Sun, Juan, Chen, Shan, Kang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822346/ https://www.ncbi.nlm.nih.gov/pubmed/31666131 http://dx.doi.org/10.1186/s13148-019-0748-4

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