Induction of Stearoyl-CoA 9-Desaturase 1 Protects Human Mesenchymal Stromal Cells Against Palmitic Acid-Induced Lipotoxicity and Inflammation

In bone diseases such as osteonecrosis and osteoporosis, a shift toward a preferential differentiation of mesenchymal stromal cells (MSC) into adipocytes at the expense of the osteoblastic lineage is described, leading to excessive accumulation of adipocytes in the bone marrow of the patients. The i...

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Detalles Bibliográficos
Autores principales: Dalla Valle, Antoine, Vertongen, Pascale, Spruyt, Delphine, Lechanteur, Jessica, Suain, Valérie, Gaspard, Nathalie, Brion, Jean-Pierre, Gangji, Valérie, Rasschaert, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822410/
https://www.ncbi.nlm.nih.gov/pubmed/31708874
http://dx.doi.org/10.3389/fendo.2019.00726

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