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Optimizing sequencing protocols for leaderboard metagenomics by combining long and short reads
As metagenomic studies move to increasing numbers of samples, communities like the human gut may benefit more from the assembly of abundant microbes in many samples, rather than the exhaustive assembly of fewer samples. We term this approach leaderboard metagenome sequencing. To explore protocol opt...
Autores principales: | Sanders, Jon G., Nurk, Sergey, Salido, Rodolfo A., Minich, Jeremiah, Xu, Zhenjiang Z., Zhu, Qiyun, Martino, Cameron, Fedarko, Marcus, Arthur, Timothy D., Chen, Feng, Boland, Brigid S., Humphrey, Greg C., Brennan, Caitriona, Sanders, Karenina, Gaffney, James, Jepsen, Kristen, Khosroheidari, Mahdieh, Green, Cliff, Liyanage, Marlon, Dang, Jason W., Phelan, Vanessa V., Quinn, Robert A., Bankevich, Anton, Chang, John T., Rana, Tariq M., Conrad, Douglas J., Sandborn, William J., Smarr, Larry, Dorrestein, Pieter C., Pevzner, Pavel A., Knight, Rob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822431/ https://www.ncbi.nlm.nih.gov/pubmed/31672156 http://dx.doi.org/10.1186/s13059-019-1834-9 |
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