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Wild-type menin is rapidly degraded via the ubiquitin-proteasome pathway in a rat insulinoma cell line
Menin is encoded by multiple endocrine neoplasia type 1 (MEN1) gene, the germ line mutations of which are the main cause of pancreatic neuroendocrine tumors (PNETs). To date, a large number of frameshift, nonsense and missense mutations of MEN1 have been identified to be responsible for part of MEN1...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822493/ https://www.ncbi.nlm.nih.gov/pubmed/31652443 http://dx.doi.org/10.1042/BSR20190471 |