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High-throughput sequencing analysis of genes encoding the B-lymphocyte receptor heavy-chain CDR3 in renal and peripheral blood of IgA nephropathy

Aim: IgA nephropathy (IgAN) is one of the most common chronic glomerulonephritis. Its etiology and pathogenesis remain unclear. We thus explored the immune repertoire of the B-cell receptor (BCR) and the heavy-chain complementarity-determining region 3 (CDR3) in renal tissue and peripheral blood of...

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Detalles Bibliográficos
Autores principales: Chen, Dapeng, Zhang, Zheng, Yang, Yue, Hong, Quan, Li, Wenge, Zhuo, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822498/
https://www.ncbi.nlm.nih.gov/pubmed/31551340
http://dx.doi.org/10.1042/BSR20190482

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