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Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats

An aspalathin-rich green rooibos extract (Afriplex GRT™) has demonstrated anti-diabetic and hypolipidemic properties, while also moderately inhibiting CYP3A4 activity, suggesting a potential for herb–drug interaction. The present study, therefore, evaluated the effects of orally administered GRT on...

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Detalles Bibliográficos
Autores principales:	Patel, Oelfah, Muller, Christo J.F., Joubert, Elizabeth, Rosenkranz, Bernd, Taylor, Malcolm J.C., Louw, Johan, Awortwe, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822546/ https://www.ncbi.nlm.nih.gov/pubmed/31708777 http://dx.doi.org/10.3389/fphar.2019.01243

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